Pseudorabies virus gB (PRV-gB) Nucleic Acid Test Kit (Lyophilized)

Clinical Applications

1. Vaccine Efficacy Monitoring in Swine Farms：In swine farms that have implemented PRV vaccination programs, the PRV - gB nucleic acid detection reagent for vaccine - strain can be used to monitor the efficacy of the vaccine. After vaccination, by collecting samples such as nasal swabs or blood from pigs at different time - points, veterinarians can detect the presence and quantity of the vaccine - strain virus in the pigs. If the detection shows a proper level of the vaccine - strain virus in the early stage after vaccination, it indicates that the vaccine has been successfully delivered and is stimulating the immune response. However, if the vaccine - strain virus is not detected or the quantity is extremely low, it may suggest issues with the vaccination process, such as improper vaccine storage or ineffective vaccination methods.

2. Differentiating Vaccine - Strain from Wild - Type Virus：Although the vaccine - strain PRV is designed to be attenuated, it is important to distinguish it from the wild - type virus to ensure accurate disease diagnosis and effective control. In cases where pigs show symptoms that may be related to PRV infection, using this reagent to detect the vaccine - strain gB gene first can rule out wild - type virus infection if only the vaccine - strain is detected. This helps in accurately determining the cause of the symptoms and taking appropriate measures. For example, if a vaccinated pig shows mild respiratory symptoms, detecting the vaccine - strain gB gene can confirm that it may be a normal reaction to the vaccine rather than a wild - type virus - induced disease.

3. Quality Control of Vaccines：For vaccine manufacturers, the PRV - gB nucleic acid detection reagent for vaccine - strain is an important tool for quality control. During the vaccine production process, it can be used to ensure that the vaccine contains the correct amount of the vaccine - strain virus. By testing the vaccine samples at different production stages, manufacturers can monitor the consistency and quality of the vaccine. If the gB nucleic acid content of the vaccine - strain in the final product does not meet the standard, it may affect the vaccine's effectiveness, and the production process needs to be adjusted accordingly.

4. Research on Vaccine - Strain Viral Behavior：In scientific research related to PRV vaccines, this detection reagent provides valuable support. It allows researchers to study the replication, distribution, and persistence of the vaccine - strain virus in pigs. By analyzing a large number of samples from vaccinated pigs over time, researchers can gain a deeper understanding of how the vaccine - strain virus interacts with the pig's immune system, which is crucial for the development of more efficient and safer PRV vaccines.