Peste Petit Ruminant Virus Wild Strain (PPRV-W) Nucleic Acid Test Kit (Lyophilized)

Symptoms 

• Fever and General Malaise: Infected small ruminants, such as goats and sheep, typically experience a sudden onset of high fever, often reaching up to 40 - 41°C. This is accompanied by general weakness, lethargy, and a significant loss of appetite. The animals become less active, showing a reluctance to move or graze.

• Oral and Nasal Manifestations: Nasal discharge is a common early symptom, starting as clear and gradually turning mucopurulent. There is also ocular discharge, causing the eyes to appear watery and inflamed. In the oral cavity, small erosions and ulcers develop on the mucosa, especially on the gums, tongue, and inner cheeks. These oral lesions can be extremely painful, leading to difficulty in chewing, swallowing, and even excessive salivation.

• Gastrointestinal Disorders: Severe diarrhea is a prominent symptom of PPRV - W infection. The feces are often watery and may contain mucus or blood in advanced cases. The diarrhea can cause dehydration, electrolyte imbalance, and further weight loss. Additionally, there may be abdominal pain, which can be observed through the animals' restless behavior.

• Respiratory Distress: As the disease progresses, respiratory symptoms become more pronounced. Infected animals cough frequently, and their breathing becomes rapid and labored. The virus infects the respiratory tract, causing inflammation and congestion, which can lead to pneumonia in severe cases. The respiratory distress can be life - threatening, especially for young or immunocompromised animals.

Clinical Applications 

• Early and Precise Diagnosis: The PPRV - W nucleic acid detection reagent can accurately detect the presence of the wild - type virus in the early stages of infection. This is crucial because early diagnosis allows for immediate isolation of infected animals, minimizing the spread of the virus within the herd. For example, if a farmer notices a few goats with a slight fever and nasal discharge, using this detection reagent can quickly determine if PPRV - W is the cause.

• Epidemic Surveillance and Control: In regions where PPRV - W is a threat, regular screening of small ruminant populations using the nucleic acid detection reagent is essential for epidemic surveillance. By detecting subclinical carriers and early - stage infections, veterinarians and livestock authorities can implement targeted control measures, such as vaccination campaigns, quarantine of affected areas, and culling of infected animals if necessary.

• Differential Diagnosis: Since the symptoms of PPRV - W infection can overlap with those of other diseases in small ruminants, like peste des petits ruminants vaccine - related reactions or other viral and bacterial infections, the nucleic acid detection reagent plays a vital role in accurate differential diagnosis. It can specifically identify the PPRV - W strain, ensuring that the correct treatment and prevention strategies are employed.

• Trade - related Quarantine: In the international and domestic trade of small ruminants, the PPRV - W nucleic acid detection reagent is used for quarantine purposes. It helps to ensure that the animals being traded are free from the wild - type virus, preventing the introduction and spread of PPRV - W across different regions. This is crucial for maintaining the health of disease - free areas and protecting the livestock industry from economic losses associated with PPRV - W outbreaks.