Fluorescence detection has significant clinical value for Markers of diabetic nephropathy. Clinically, it can sensitively detect specific biomarkers related to this condition, like albuminuria and neutrophil gelatinase-associated lipocalin. By accurately quantifying these markers, doctors can identify the onset and progression of diabetic nephropathy at an early stage. This allows for timely intervention, such as adjusting diabetes management and initiating kidney-protective therapies. Moreover, during treatment, fluorescence detection helps monitor the effectiveness of interventions by tracking changes in marker levels, optimizing care and potentially delaying the disease's advance.